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This reinforces what weve seen across other studies and in real-world practice, says Yuval Pinto, MD, an obesity and family medicine doctor at Johns Hopkins Medicine in Baltimore, who was not involved in the research

Prioritizing the development of gene therapy tools that are more precise, efficient, minimally off-target, safer, and easier to deliver is essential

Diabetes GLP-1s fare better due to broader coverage and disease framing, but still face meaningful leakage

Unlike dietary L-carnitine obtained from red meat, which the body absorbs highly efficiently, oral L-carnitine supplements have a relatively low absolute bioavailability, typically ranging from 14% to 18%